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Distinct from other prescription slimming pills Xenical uses a fat blocking mode of action that works non-systemically in the gastrointestinal tract. Dietary fats are large molecules that must be broken down by enzymes, called lipases, before they can be absorbed into the bloodstream. Xenical slimming pills interfere with these lipases by forming covalent bonds with them in the stomach and small intestine, this essentially inactivates the enzymes so they are are no longer available to hydrolyze dietary fat into an absorbable state. Thus, allowing for some 30% of dietary fats to pass though the gastrointestinal tract without being absorbed. Again, this reduces the caloric intake by some 30% promoting slimming.


Xencial is the only prescription slimming pill, "fat blocker," that reduces caloric intake from fats by some 30% promoting slimming:


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